Welcome to the Patel Lab
Uncovering circuit mechanisms of mental health disorders
Our goal is to understand how neuroimmune mechanisms and social factors interact with neural circuits contributing to mental health disorders.
We use a multidisciplinary approach to gain mechanistic insight into the brain, including:
-
Molecular Biology
To visualize cellular-level gene expression
-
Patch-Clamp Electrophysiology
To assess synaptic-level transmission between neurons
-
Circuit Manipulation
To dissect circuit-level connectivity underlying behavior
-
In Vivo Calcium Imaging
To measure cellular-level neural dynamics during behavior
-
Cell-Type Sequencing
To explore glial and neuronal transcriptomic signatures of experience
-
Rodent Behavior
To investigate endophenotypes associated with mental health disorders